EQUINIX INC files 424B2: prospectus (424B)

Prospectus Supplement (To Prospectus Dated October 28, 2026)

Equinix Europe 2 Financing Corporation LLC

Unconditionally Guaranteed by Equinix, Inc.

Equinix Europe 2 Financing Corporation LLC (the “Issuer”), a Delaware limited liability company that is an indirect, wholly-owned subsidiary of Equinix, Inc., is offering 650,000,000 aggregate principal amount of 4.150% Senior Notes due 2028 (the “2028 notes”), 700,000,000 aggregate principal amount of 4.800% Senior Notes due 2033 (the “2033 notes”), 500,000,000 aggregate principal amount of 5.100% Senior Notes due 2035 (the “2035 notes”) and 650,000,000 aggregate principal amount of 5.450% Senior Notes due 2038 (the “2038 notes” and, together with the 2028 notes, the 2033 notes and the 2035 notes, the “notes”). Interest will accrue on each series of notes from November 9, 2026. Interest on the 2028 notes will be payable annually on November 9 of each year, commencing on November 9, 2027.

Interest on the 2033 notes will be payable annually on February 15 of each year, commencing on February 15, 2027. Interest on the 2035 notes will be payable annually on November 9 of each year, commencing on November 9, 2027. Interest on the 2038 notes will be payable annually on November 9 of each year, commencing on November 9, 2027. The Issuer may redeem any series of the notes in whole or in part at any time or from time to time at the redemption prices described under “Description of Notes — Optional Redemption,” which include accrued and unpaid interest thereon, if any, to, but not including, the applicable redemption date. Depending on when such notes are redeemed, a make-whole premium may or may not be payable in respect of any such redemptions.

The notes will be fully and unconditionally guaranteed on an unsecured basis by Equinix, Inc., a Delaware corporation.

The notes will be the Issuer’s unsecured senior obligations and will rank equal in right of payment to all of the Issuer’s existing and future unsecured and unsubordinated indebtedness and structurally subordinated to all of the liabilities of the Issuer’s subsidiaries, if any. In addition, Equinix, Inc.’s obligations under the guarantees will rank equally with all of its other unsecured and unsubordinated indebtedness and will be effectively subordinated to all of the existing and future secured indebtedness of Equinix, Inc. and structurally subordinated to all of the indebtedness and liabilities of other subsidiaries of Equinix, Inc. Upon a change of control triggering event, the Issuer will be required to make an offer to purchase each holder’s notes at a purchase price equal to 101% of the aggregate principal amount thereof plus accrued and unpaid interest if any, to but not including, the date of purchase.

The Issuer intends to apply to list each series of notes on the Nasdaq Bond Exchange. The Issuer expects trading in the notes on the Nasdaq Bond Exchange to begin within 30 days after their original issue date. Currently, there is no public market for the notes.

We estimate that the net proceeds from the sale of the notes offered hereby, after deducting the underwriting discounts and estimated offering expenses payable by us, will be approximately 2.5 billion. We intend to allocate an amount equal to the net proceeds from this offering to finance or refinance, in whole or in part, one or more Eligible Green Projects (as defined in “Use of Proceeds”). Pending full allocation of an amount equal to the net proceeds of the offering of the notes, the net proceeds may be used in accordance with our general treasury policy and be held in cash, cash equivalents and U.S. government securities or used to repay existing borrowings. We will not knowingly invest any unallocated proceeds in securities directly related to fossil fuels. Payment of principal and interest on the notes will be made from our general account and will not be linked to the performance of the Eligible Green Projects.

The following is a brief summary of certain terms of this offering. For a more complete description of the terms of the notes offered hereby, see “Description of Notes” in this prospectus supplement and the section titled “Description of Debt Securities” in the accompanying prospectus.

Issuer

Equinix Europe 2 Financing Corporation LLC, a Delaware limited liability company.

Guarantor Equinix, Inc., a Delaware corporation.

Notes Offered 650,000,000 aggregate principal amount of the 2028 notes;

700,000,000 aggregate principal amount of the 2033 notes;

500,000,000 aggregate principal amount of the 2035 notes;

and 650,000,000 aggregate principal amount of the 2038 notes.

Maturity Dates

November 9, 2028 for the 2028 notes, February 15, 2033 for the 2033 notes, November 9, 2035 for the 2035 notes and November 9, 2038 for the 2038 notes.

Interest

The 2028 notes will bear interest from November 9, 2026 at the rate of 4.150% per annum, the 2033 notes will bear interest from November 9, 2026 at the rate of 4.800% per annum, the 2035 notes will bear interest from November 9, 2026 at the rate of 5.100% per annum and the 2038 notes will bear interest from November 9, 2026 at the rate of 5.450% per annum.

Interest Payment Dates 2028 notes: November 9 of each year, beginning on November 9, 2027

2033 notes: February 15 of each year, beginning on February 15, 2027

2035 notes: November 9 of each year, beginning on November 9, 2027

2038 notes: November 9 of each year, beginning on November 9, 2027

Ranking

The notes will be the Issuer’s general senior obligations. Your right to payment under these notes will be:

effectively subordinated to any of the Issuer’s existing and future secured indebtedness;

structurally subordinated to any existing and future indebtedness and other liabilities (including trade payables) of any of the Issuer’s subsidiaries, if any;

As of September 30, 2026, the Issuer had no subsidiaries and $7.3 billion of outstanding indebtedness (excluding trade payables and intercompany items and liabilities of a type not required to be reflected on the balance sheet of Equinix, Inc.’s subsidiaries in accordance with U.S. generally accepted accounting principles, or GAAP).

Guarantees

The notes will be fully and unconditionally guaranteed on an unsecured basis by Equinix, Inc. Equinix, Inc.’s obligations under the guarantees will be:

effectively subordinated to all of Equinix, Inc.’s existing and future secured indebtedness;

structurally subordinated to all of the existing and future indebtedness and other liabilities (including trade payables) of other subsidiaries of Equinix, Inc.;

As of September 30, 2026, without giving effect to this offering:

Equinix, Inc. had total consolidated indebtedness of approximately $25.0 billion, approximately $14 million of which represented secured indebtedness (excluding approximately $2.4 billion of finance lease liabilities);